hypogenic-hypothesis-generation

Installation
SKILL.md

HypoGeniC Hypothesis Generation

Overview

HypoGeniC automates scientific hypothesis generation and testing using LLMs on tabular datasets. Given labeled data (e.g., deception detection, AI-content identification), it generates testable hypotheses, iteratively refines them against validation performance, and runs inference to classify new samples. It supports three approaches: purely data-driven (HypoGeniC), literature-integrated (HypoRefine), and mechanistic union of both.

When to Use

  • Generating testable hypotheses from labeled observational datasets without prior theory
  • Systematically testing multiple competing hypotheses on empirical data
  • Combining insights from research papers with data-driven pattern discovery
  • Accelerating hypothesis ideation in domains like deception detection, content analysis, mental health indicators
  • Benchmarking LLM-based hypothesis generation methods against few-shot baselines
  • For manual hypothesis formulation frameworks, use hypothesis-generation knowhow
  • For general-purpose ML classification without hypothesis interpretability, use scikit-learn-machine-learning

Prerequisites

Related skills

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Mar 16, 2026