Genomics and Transcriptomics Analysis

When to Use This Skill

• When data contains gene expression measurements (RNA-seq, microarray)
• When analyzing differential gene expression
• When performing pathway or gene set enrichment analysis
• When interpreting genetic variants or mutations

Core Concepts

Gene Expression Data Types

RNA-seq counts:

• Raw read counts per gene
• Requires normalization (TPM, RPKM, DESeq2)
• Suitable for differential expression analysis