proteinmpnn

Installation
SKILL.md

ProteinMPNN Sequence Design

Prerequisites

Requirement Minimum Recommended
Python 3.8+ 3.10
CUDA 11.0+ 11.7+
GPU VRAM 8GB 16GB (T4)
RAM 8GB 16GB

How to run

First time? See Getting started to set up Modal and biomodals.

Option 1: Local installation (recommended)

git clone https://github.com/dauparas/ProteinMPNN.git
cd ProteinMPNN
Installs
45
GitHub Stars
151
First Seen
Jan 21, 2026
proteinmpnn — adaptyvbio/protein-design-skills