ESTIMATE Immune Score Analysis

When to Use

Use this skill when the user wants to:

• compute ESTIMATE-derived immune and stromal scores from a bulk expression matrix
• transform an expression matrix into estimate package input files and score outputs
• generate an ESTIMATE score heatmap across samples
• compare ESTIMATE scores across sample groups when a sample group file is available
• create a reproducible CLI-backed ESTIMATE workflow with structured output records

Typical request patterns:

• "Run ESTIMATE immune score analysis on this expression matrix"
• "Calculate ImmuneScore and StromalScore from my bulk RNA-seq data"
• "Generate ESTIMATE scores and save a sample-level result table"

Execution Model