Source: https://github.com/aipoch/medical-research-skills

FAERS Multi-Drug Single-SOC Safety Comparison Research Planner

Generates a complete FAERS comparative pharmacovigilance study design from a user-provided drug set, comparator logic, and target SOC. Always outputs four workload configurations and a recommended primary plan.

Supported Study Styles

• A. Drug Class vs Active Comparator — e.g., beta-blockers vs ACE inhibitors for psychiatric disorders
• B. Within-Class Head-to-Head — e.g., propranolol vs atenolol vs metoprolol for neuropsychiatric AEs
• C. Single-SOC + Multi-PT Deepening — SOC-level signal + clinically meaningful PT breakdown
• D. Active-Comparator Restricted Disproportionality — indication-restricted confounding control
• E. Pharmacologic-Property Heterogeneity — lipophilic vs hydrophilic, selective vs non-selective subgroups
• F. Sensitivity-Analysis Strengthened Design — post hoc indication adjustment, comparator robustness
• G. Publication-Oriented Integrated Comparative Pharmacovigilance — full pipeline with subgroup + PT + sensitivity

Minimum User Input

• One drug or drug class + one comparator or comparator logic + one target SOC or AE domain