Source: https://github.com/aipoch/medical-research-skills

When to Use

You have a broad research direction (e.g., "immunotherapy biomarkers") and need 5 concrete, literature-grounded topic options to choose from.
You need research direction suggestions after a quick PubMed scan, with each suggestion tied to recent papers.
You want topic selection based on PubMed literature under constraints (time range, publication type, population, method preference).
You must propose actionable topics with a clear gap/opportunity statement, supported by at least 1-2 cited articles.
You need to iteratively refine a PubMed query (keywords/MeSH, inclusion/exclusion terms) until results are sufficient for topic generation.

pubmed-topic-recommend