ROC Diagnostic Performance

When to Use

Use this skill when you need to:

• evaluate one or more diagnostic marker genes in a case-control cohort;
• build a multivariable logistic regression diagnostic model from marker expression values;
• compare the ROC performance of the full model against individual markers.

Typical user requests:

• "Use these genes to build a diagnostic ROC model for case vs control samples."
• "Evaluate the AUC of FOXP3, CD45, and CD3E and plot all ROC curves together."
• "Run logistic regression on biomarker expression and export ROC results."

When Not to Use