string-database

Installation
SKILL.md

Source: https://github.com/aipoch/medical-research-skills

When to Use

  • You have gene symbols (e.g., TP53) and need to resolve them to STRING protein identifiers for downstream analysis.
  • You want to retrieve a protein–protein interaction (PPI) network (functional/physical) with confidence scores for one or more proteins.
  • You need to find interaction partners for a target protein to expand a candidate list (e.g., add top N neighbors).
  • You want to perform functional enrichment (GO/KEGG/Reactome, etc.) for a protein set to interpret biological themes.
  • You need a quick static visualization (PNG/SVG) of a STRING network for reports or notebooks.

Key Features

  • ID Mapping: Convert gene/protein names to STRING identifiers for a given organism.
  • Network Retrieval: Fetch interaction edges with confidence scores from STRING.
  • Interaction Partners: Expand a protein list by retrieving interaction partners.
  • Enrichment Analysis:
    • Functional enrichment (e.g., GO, KEGG, Reactome)
    • PPI enrichment statistics
    • Functional annotations (e.g., PFAM/SMART where supported by STRING endpoints)
  • Visualization: Download static network images (PNG/SVG).
Installs
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GitHub Stars
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First Seen
Sep 23, 2026
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