Genomics Analysis (Meta Skill)

This meta-skill coordinates a complete genomics analysis pipeline by integrating gene database queries, sequence analysis, expression profiling, and pathway enrichment into a unified workflow. It combines three specialized skills to deliver comprehensive gene-level and systems-level biological insights.

Workflow

Step 1: Gene Information Retrieval

Query NCBI Entrez for comprehensive gene details including official nomenclature, genomic coordinates, transcript variants, and functional annotations. Retrieve orthologs across model organisms for evolutionary context. Pull known variants from ClinVar and dbSNP, noting pathogenic or pharmacogenomic associations. Collect linked references from PubMed for recent literature context.

Step 2: Sequence Analysis