string-database

Installation
SKILL.md

STRING Database

Overview

STRING is a comprehensive database of known and predicted protein-protein interactions covering 59M proteins and 20B+ interactions across 5000+ organisms. Query interaction networks, perform functional enrichment, discover partners via REST API for systems biology and pathway analysis.

When to Use This Skill

This skill should be used when:

  • Retrieving protein-protein interaction networks for single or multiple proteins
  • Performing functional enrichment analysis (GO, KEGG, Pfam) on protein lists
  • Discovering interaction partners and expanding protein networks
  • Testing if proteins form significantly enriched functional modules
  • Generating network visualizations with evidence-based coloring
  • Analyzing homology and protein family relationships
  • Conducting cross-species protein interaction comparisons
  • Identifying hub proteins and network connectivity patterns

Quick Start

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