Field	Type	Required	Notes
`condition`	string	no	Condition or disease
`intervention`	string	no	Drug, device or procedure
`sponsor`	string	no	Lead sponsor or collaborator
`term`	string	no	Free-text search across the record
`status`	string	no	One of RECRUITING, NOT_YET_RECRUITING, ACTIVE_NOT_RECRUITING, ENROLLING_BY_INVITATION, COMPLETED, SUSPENDED, TERMINATED, WITHDRAWN, AVAILABLE, NO_LONGER_AVAILABLE, TEMPORARILY_NOT_AVAILABLE, APPROVED_FOR_MARKETING, WITHHELD, UNKNOWN
`phase`	string	no	One of EARLY_PHASE1, PHASE1, PHASE2, PHASE3, PHASE4
`limit`	number	no	1-50, default 10

Example input:

{
  "condition": "melanoma",
  "status": "RECRUITING",
  "limit": 5
}

Metered

The 402 quotes a ceiling — the price of the declared cap, 50 results — and settlement is for what the call actually used. A small request settles for less than it was quoted, so read the quote as an upper bound rather than a price.

Cost and provenance


Price	$0.004 per call, metered per results
Source	ClinicalTrials.gov API v2 (NIH/NLM), public domain
Licence	public-domain

Why call it rather than answer from memory

A clinical, diligence or patient-facing agent needs the trials open right now for a condition, and recruitment status changes weekly so training data is always stale.

Calling it

A skill is loaded on its own, so this document has to be enough by itself. It does not assume the general fittings skill is also loaded. call.mjs ships alongside this file; if it is missing (this document reached you without the rest of the skill), fetch it once with curl -sO https://fittings.sh/skill/call.mjs.

Free, and needs no wallet. Read the schema and see what a call would cost:

curl -s https://fittings.sh/catalog/ctgov.trial-search | jq

Paying. The endpoint answers 402 Payment Required with a signed quote, you sign an authorization, and a facilitator settles it — you never send a transaction and never pay gas. Before it spends anything, the client checks its own hash against the gateway and refuses rather than sign with logic the gateway has moved past:

# Dry run. Prints the quote and pays nothing, because no key is set.
node call.mjs ctgov.trial-search condition=melanoma status=RECRUITING limit=5

# For real: a wallet holding USDC on Base, and nothing else.
export FITTINGS_PRIVATE_KEY=0x...
node call.mjs ctgov.trial-search condition=melanoma status=RECRUITING limit=5

Spending is never a side effect of curiosity: with no FITTINGS_PRIVATE_KEY the client fetches the quote and stops. FITTINGS_MAX_PRICE caps what it will pay without asking, and defaults to $0.05.

Use a throwaway wallet holding a few dollars, not a main one. The key sits in plaintext wherever the agent runs, and the whole cost of entry is USDC on Base — no account, no API key, and no ETH, because the payer signs off-chain and the facilitator broadcasts and pays the gas.

Writing your own client instead of using this one? @x402/core and @x402/evm on npm, and the fittings skill records the two things that cost real debugging time: the challenge is in a response header rather than the body, and it must be re-signed from the exact request being retried.

If this is not the right service, https://fittings.sh/catalog/search?q=... searches all of them for free.

fittings-ctgov-trial-search

ClinicalTrials.gov trial search

The call