tooluniverse-variant-interpretation

Pass

Audited by Gen Agent Trust Hub on Jul 30, 2026

Risk Level: SAFE
Full Analysis
  • [EXTERNAL_DOWNLOADS]: Retrieves variant annotations and clinical evidence from well-known technology and scientific services including ClinVar, gnomAD, UniProt, and the Protein Data Bank (PDB).
  • [COMMAND_EXECUTION]: Utilizes platform-provided tools for specialized bioinformatics computations, such as SpliceAI for splicing analysis and AlphaFold2 for protein structure prediction via NVIDIA NIM.
  • [SAFE]: Secret management for external API access (e.g., OMIM_API_KEY, NVIDIA_API_KEY) correctly utilizes environment variables rather than hardcoding credentials, adhering to security best practices.
  • [SAFE]: The skill processes data from external literature sources like PubMed and preprint servers (bioRxiv/medRxiv). While this constitutes a data ingestion surface, the skill implements systematic evidence grading and verification checklists to ensure the reliability of the clinical output.
Audit Metadata
Risk Level
SAFE
Analyzed
Jul 30, 2026, 03:10 AM