alphagenome-variant-impact-score

Pass

Audited by Gen Agent Trust Hub on Sep 16, 2026

Risk Level: SAFEEXTERNAL_DOWNLOADSINDIRECT_PROMPT_INJECTION
Full Analysis
  • [EXTERNAL_DOWNLOADS]: The skill downloads a GENCODE v46 GTF reference dataset in Feather format from a Google Cloud Storage bucket (storage.googleapis.com/alphagenome). This is a legitimate vendor resource used for gene structure analysis.
  • [INDIRECT_PROMPT_INJECTION]: The skill ingests and processes genomic variant data from external files (VCF, CSV, TSV, Parquet) which could theoretically contain malicious instructions.
  • Ingestion points: Input variant files processed by scripts/alphagenome_atlas_avi.py via the annotate, query, and region subcommands.
  • Boundary markers: Absent.
  • Capability inventory: Performs gRPC network requests to the AlphaGenome Atlas API and executes local file system reads/writes for genomic data.
  • Sanitization: Input data is strictly parsed into structured VariantRecord objects using specialized libraries (pysam, polars), which effectively sanitizes the input for its intended scientific use case.
Audit Metadata
Risk Level
SAFE
Analyzed
Sep 16, 2026, 05:58 AM