Drug-Drug Interaction (DDI) Evidence-Based Assessment

Overview

This skill implements a Retrieval-Augmented Generation (RAG) approach to drug-drug interaction assessment, modeled after the Micromedex Drug-Reax System methodology. Rather than relying on LLM training data alone -- which may be outdated, incomplete, or hallucinated -- every claim in the output is grounded in real-time literature retrieval from peer-reviewed sources with full citation traceability. The structured report mirrors Micromedex Drug-Reax classification grades and is designed to complement (not replace) certified drug information systems and clinical pharmacist expertise.

Trigger

• /drug-drug DrugA DrugB
• Any query mentioning two drug names and asking about interaction, safety, or concomitant use
• Keywords: DDI, interaction, contraindication, concomitant, 交互作用, 併用