sgrna-design-guide

Pass

Audited by Gen Agent Trust Hub on Sep 18, 2026

Risk Level: SAFEEXTERNAL_DOWNLOADSCOMMAND_EXECUTIONINDIRECT_PROMPT_INJECTION
Full Analysis
  • [EXTERNAL_DOWNLOADS]: Fetches pre-computed sgRNA datasets from the Broad Institute's CRISPick web tool portal, which is a well-known and reputable research service.
  • [COMMAND_EXECUTION]: Instructs the agent to use wget and gunzip shell commands to download and extract genomic datasets. These operations are directly associated with the skill's primary purpose of data acquisition for design analysis.
  • [INDIRECT_PROMPT_INJECTION]: The skill is designed to process untrusted data from literature searches and external datasets.
  • Ingestion points: Untrusted content enters the agent context through the advanced_web_search_claude tool results and downloaded CRISPick files.
  • Boundary markers: The skill does not define specific delimiters or instructions to ignore embedded prompts within the ingested data.
  • Capability inventory: The skill utilizes shell commands (wget, gunzip) and Python data processing libraries to manipulate files.
  • Sanitization: No explicit sanitization or filtering of external data content is implemented.
Audit Metadata
Risk Level
SAFE
Analyzed
Sep 18, 2026, 12:55 AM