cbioportal-database
cBioPortal Database
Overview
cBioPortal for Cancer Genomics (https://www.cbioportal.org/) is an open-access resource for exploring, visualizing, and analyzing multidimensional cancer genomics data. It hosts data from The Cancer Genome Atlas (TCGA), AACR Project GENIE, MSK-IMPACT, and hundreds of other cancer studies — covering mutations, copy number alterations (CNA), structural variants, mRNA/protein expression, methylation, and clinical data for thousands of cancer samples.
Key resources:
- cBioPortal website: https://www.cbioportal.org/
- REST API: https://www.cbioportal.org/api/
- API docs (Swagger): https://www.cbioportal.org/api/swagger-ui/index.html
- Python client:
bravadoorrequests - GitHub: https://github.com/cBioPortal/cbioportal
When to Use This Skill
Use cBioPortal when:
- Mutation landscape: What fraction of a cancer type has mutations in a specific gene?
- Oncogene/TSG validation: Is a gene frequently mutated, amplified, or deleted in cancer?
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