primekg
PrimeKG Knowledge Graph Skill
Overview
PrimeKG is a precision medicine knowledge graph that integrates over 20 primary databases and high-quality scientific literature into a single resource. It contains over 100,000 nodes and 4 million edges across 29 relationship types, including drug-target, disease-gene, and phenotype-disease associations.
Key capabilities:
- Search for nodes (genes, proteins, drugs, diseases, phenotypes)
- Retrieve direct neighbors (associated entities and clinical evidence)
- Analyze local disease context (related genes, drugs, phenotypes)
- Identify drug-disease paths (potential repurposing opportunities)
Data access: Programmatic access via query_primekg.py. Data is stored at C:\Users\eamon\Documents\Data\PrimeKG\kg.csv.
When to Use This Skill
This skill should be used when:
- Knowledge-based drug discovery: Identifying targets and mechanisms for diseases.
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