protein-assembly
Protein Assembly Skill
This skill provides structured guidance for designing fusion protein gBlock sequences that combine multiple protein components (antibody fragments, fluorescent proteins, enzyme domains) into a single optimized DNA construct.
When to Use This Skill
This skill applies to tasks that involve:
- Designing fusion proteins from multiple sources (PDB, plasmids, protein databases)
- Creating gBlock sequences with specific linker requirements
- Codon optimization for GC content constraints
- Combining fluorescent proteins with specific excitation/emission wavelengths
- Assembling multi-domain proteins with N-terminal methionine removal
Structured Approach
Phase 1: Information Gathering and Cataloging
Objective: Collect ALL required sequence data before any design work begins.
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