Fit SimBiology Models

Estimate parameters from data using fitproblem, fit population models with NLME, generate virtual patients, and compute NCA metrics.

When to Use

• "fit", "estimate", "calibrate" model parameters
• Parameter estimation from experimental/observed data
• Population PK/PD, NLME, mixed effects, inter-individual variability
• Virtual patients, virtual cohorts
• NCA, AUC, Cmax, Tmax, half-life, clearance
• Keywords: "fit", "estimate", "calibrate", "population", "NCA", "AUC"

When NOT to Use

• Model construction or diagram (use matlab-build-simbiology-model)
• Simulation without fitting (use matlab-simulate-simbiology-model)
• Sensitivity analysis (use matlab-simulate-simbiology-model)