tooluniverse-biomedical-fact-lookup

Installation
SKILL.md

Biomedical Fact Lookup (tool-grounded answering)

Factual biomedical questions — "which gene is in set X", "which gene is associated with disease Y according to DisGeNet", "which gene has a TF binding site per GTRD" — have an authoritative answer in a public database. Guessing from memory is unreliable (≈chance on niche annotations); the matching ToolUniverse tool returns the ground truth.

Six traps that produce a confidently wrong answer

Each was observed producing a wrong answer on a real question. Check them before answering; the detail for each is further down.

  1. "Highest p-value" in GWAS means most significant — the smallest number. Read literally it picks the study's weakest hit (rs2476491 at 1e-06 instead of rs7775055-G at 3e-174).

  2. A window of "N bp upstream plus M bp downstream" spans N+M+1 bases — the anchor counts. 100 either side of a TSS is 201 nt, not 200. Check the length you got against the length you asked for.

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First Seen
Jul 7, 2026
tooluniverse-biomedical-fact-lookup — mims-harvard/tooluniverse