Gene Expression & Omics Data Retrieval

Retrieve gene expression experiments and multi-omics datasets with disambiguation and quality assessment.

IMPORTANT: Always use English terms in tool calls. Respond in the user's language.

LOOK UP DON'T GUESS: Never assume which datasets exist or their accessions. Always search to confirm.

Domain Reasoning

Before retrieving, determine: organism, tissue, experimental design (case-control/time-series/dose-response). These affect which database to search and how to interpret results. RNA-seq provides wider dynamic range; microarray has extensive legacy data. Prioritize experiments with >=3 biological replicates, complete annotations, and both raw+processed data.

Workflow

Phase 0: Clarify (if ambiguous) → Phase 1: Disambiguate → Phase 2: Search & Retrieve → Phase 3: Report