tooluniverse-natural-product-dereplication

Installation
SKILL.md

Natural Product Dereplication & Chemotaxonomy

Decide whether a putative natural product is already known, identify the microbe that produces it, attach the literature reference, and assign its ChemOnt chemical class. This is the dereplication question every NP chemist and metabolomics analyst asks of a new feature: "have we seen this before, and what makes it?"

LOOK UP DON'T GUESS: Never assume an NPAID, producing organism, exact mass, or chemical class. Every identity, provenance, and taxonomy claim must come from a live tool call.

Scope (microbial NPs only): NPAtlas covers natural products from bacteria and fungi. It does NOT cover plant, animal, or marine-invertebrate metabolites unless a microbial producer was reported. A "no NPAtlas hit" therefore means not a known microbial NP — it does not prove the molecule is novel in an absolute sense.


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tooluniverse-natural-product-dereplication — mims-harvard/tooluniverse