COMPUTE, DON'T DESCRIBE

When analysis requires computation (statistics, data processing, scoring, enrichment), write and run Python code via Bash. Don't describe what you would do — execute it and report actual results. Use ToolUniverse tools to retrieve data, then Python (pandas, scipy, statsmodels, matplotlib) to analyze it.

Pharmacogenomics (PGx) Research Skill

Systematic PGx analysis: resolve gene-drug pairs, retrieve CPIC dosing guidelines, annotate alleles and variants with PharmGKB, check FDA PGx biomarker labeling, and generate evidence-graded clinical recommendations.

When to Use

• "What CPIC guidelines exist for CYP2D6?"
• "Get dosing recommendations for codeine based on CYP2D6 poor metabolizer status"
• "Which drugs have FDA pharmacogenomic biomarkers for CYP2C19?"
• "Find PharmGKB clinical annotations for rs1799853"
• "Is this patient's CYP2D6 genotype relevant to tamoxifen dosing?"
• "What is the functional status of CYP2D6*4?"
• "List all CPIC level A gene-drug pairs for CYP2D6"

Workflow Overview