tooluniverse-spatial-transcriptomics
Spatial Transcriptomics Analysis
Comprehensive analysis of spatially-resolved transcriptomics data to understand gene expression patterns in tissue architecture context. Combines expression profiling with spatial coordinates to reveal tissue organization, cell-cell interactions, and spatially variable genes.
LOOK UP, DON'T GUESS
When uncertain about any scientific fact, SEARCH databases first rather than reasoning from memory. A database-verified answer is always more reliable than a guess.
When to Use This Skill
Triggers:
- User has spatial transcriptomics data (Visium, MERFISH, seqFISH, etc.)
- Questions about tissue architecture or spatial organization
- Spatial gene expression pattern analysis
- Cell-cell proximity or neighborhood analysis requests
- Tumor microenvironment spatial structure questions
- Integration of spatial with single-cell data
- Spatial domain identification
- Tissue morphology correlation with expression
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