protein-binder-design
Installation
SKILL.md
Protein Binder Design (workflow)
Run a de novo binder design campaign by composing atomic NIM skills. This skill
owns orchestration, handoff contracts, filtering, validation, and the run
manifest. It does NOT duplicate per-NIM API details — defer those to each
atomic skill's SKILL.md.
Composed skills
| Step | Skill | Owns |
|---|---|---|
| Backbones | rfdiffusion-nim |
binder backbone PDBs (contigs + hotspots) |
| Sequences | proteinmpnn-nim |
sequences for each backbone |
| Co-fold / score | boltz2-nim or openfold3-nim |
binder–target complex + confidence / ipTM |
| MSA (optional) | msa-search-nim |
target A3M for higher-quality folding |