Operating rules

Use scripts/rest_request.py for all BindingDB API calls.
Use base_url=https://bindingdb.org.
Add response=application/json in params when you want structured output; some empty-result cases may still return an empty body.
For broad lookup endpoints, start around max_items=10; similarity-style queries are better with 5-10.
Re-run requests in long conversations instead of relying on older tool output.
Treat displayed ... in tool previews as UI truncation, not literal request content.

Execution behavior

Return concise markdown summaries from the script JSON by default.
Prefer these paths: rest/getLigandsByPDBs, rest/getLigandsByUniprots, rest/getLigandsBySmiles, and rest/getTargetsByCompound.
If the user needs the full payload, set save_raw=true and report the saved file path instead of pasting large response bodies into chat.