BindingDB Database

Overview

BindingDB (https://www.bindingdb.org/) is the primary public database of measured drug-protein binding affinities. It contains over 3 million binding data records for ~1.4 million compounds tested against ~9,200 protein targets, curated from scientific literature and patent literature. BindingDB stores quantitative binding measurements (Ki, Kd, IC50, EC50) essential for drug discovery, pharmacology, and computational chemistry research.

Key resources:

• BindingDB website: https://www.bindingdb.org/
• REST API: https://www.bindingdb.org/axis2/services/BDBService
• Downloads: https://www.bindingdb.org/bind/chemsearch/marvin/Download.jsp
• GitHub: https://github.com/drugilsberg/bindingdb

When to Use This Skill

Use BindingDB when: