skills/smithery.ai/bio-atac-seq-differential-accessibility

bio-atac-seq-differential-accessibility

Installation
SKILL.md

Version Compatibility

Reference examples tested with: DESeq2 1.42+, GenomicRanges 1.54+, Subread 2.0+, numpy 1.26+, pandas 2.2+, scanpy 1.10+, scipy 1.12+

Before using code patterns, verify installed versions match. If versions differ:

  • Python: pip show <package> then help(module.function) to check signatures
  • R: packageVersion('<pkg>') then ?function_name to verify parameters
  • CLI: <tool> --version then <tool> --help to confirm flags

If code throws ImportError, AttributeError, or TypeError, introspect the installed package and adapt the example to match the actual API rather than retrying.

Differential Accessibility

"Find differentially accessible regions between my conditions" → Identify chromatin regions with statistically significant changes in accessibility between treatment groups, cell types, or timepoints.

  • R: DiffBind or DESeq2 on a peak-by-sample count matrix

DiffBind Workflow

Installs
1
First Seen
Mar 26, 2026
bio-atac-seq-differential-accessibility from smithery.ai