Version Compatibility

Reference examples tested with: SnpEff 5.2+, pandas 2.2+

Before using code patterns, verify installed versions match. If versions differ:

• Python: pip show <package> then help(module.function) to check signatures

If code throws ImportError, AttributeError, or TypeError, introspect the installed package and adapt the example to match the actual API rather than retrying.

MyVariant.info Queries

"Annotate my variants from multiple databases at once" → Query the myvariant.info aggregation API to retrieve ClinVar, gnomAD, dbSNP, COSMIC, and other annotations in a single request per variant.

• Python: myvariant.MyVariantInfo().getvariants(ids, fields='clinvar,gnomad,dbnsfp')

Required Imports