bio-multi-omics-mofa-integration
Installation
SKILL.md
Version Compatibility
Reference examples tested with: scanpy 1.10+
Before using code patterns, verify installed versions match. If versions differ:
- R:
packageVersion('<pkg>')then?function_nameto verify parameters
If code throws ImportError, AttributeError, or TypeError, introspect the installed package and adapt the example to match the actual API rather than retrying.
MOFA2 Integration
"Find shared variation across my omics layers" → Discover latent factors that capture shared and modality-specific sources of biological variation in an unsupervised manner.
- R:
MOFA2::create_mofa()→prepare_mofa()→run_mofa() - Python:
mofapy2for training,muonfor downstream
Prepare Multi-Omics Data
Goal: Load and align multiple omics matrices into a consistent format for MOFA2 input.