Version Compatibility

Reference examples tested with: DESeq2 1.42+, edgeR 4.0+, ggplot2 3.5+, scanpy 1.10+

Before using code patterns, verify installed versions match. If versions differ:

• R: packageVersion('<pkg>') then ?function_name to verify parameters

If code throws ImportError, AttributeError, or TypeError, introspect the installed package and adapt the example to match the actual API rather than retrying.

Differential miRNA Expression

"Find differentially expressed miRNAs between my conditions" → Perform statistical testing on miRNA count matrices to identify miRNAs with significant expression changes, accounting for small RNA-specific normalization considerations.

• R: DESeq2::DESeq() or edgeR::glmQLFTest() on miRNA count data

Load miRNA Count Data

library(DESeq2)