bio-tcr-bcr-analysis-mixcr-analysis
Installation
SKILL.md
Version Compatibility
Reference examples tested with: MiXCR 4.6+, pandas 2.2+
Before using code patterns, verify installed versions match. If versions differ:
- Python:
pip show <package>thenhelp(module.function)to check signatures - CLI:
<tool> --versionthen<tool> --helpto confirm flags
If code throws ImportError, AttributeError, or TypeError, introspect the installed package and adapt the example to match the actual API rather than retrying.
MiXCR Analysis
"Extract TCR/BCR clonotypes from my sequencing data" → Assemble immune receptor sequences from raw reads, identify V(D)J gene segments, and generate clonotype tables for repertoire analysis.
- CLI:
mixcr analyzefor end-to-end TCR/BCR extraction and clonotype assembly
Complete Workflow (Recommended)
Goal: Run end-to-end V(D)J alignment and clonotype assembly from raw FASTQ files in a single command.