bio-tcr-bcr-analysis-vdjtools-analysis
Installation
SKILL.md
Version Compatibility
Reference examples tested with: MiXCR 4.6+, VDJtools 1.2.1+, matplotlib 3.8+, pandas 2.2+, scanpy 1.10+
Before using code patterns, verify installed versions match. If versions differ:
- Python:
pip show <package>thenhelp(module.function)to check signatures - CLI:
<tool> --versionthen<tool> --helpto confirm flags
If code throws ImportError, AttributeError, or TypeError, introspect the installed package and adapt the example to match the actual API rather than retrying.
VDJtools Analysis
"Compute diversity and overlap for my TCR repertoires" → Calculate repertoire diversity metrics, sample overlap, and perform statistical comparisons between immune repertoire samples.
- CLI:
vdjtools CalcDiversityStats,vdjtools OverlapPair,vdjtools PlotFancySpectratype
Basic Usage
Goal: Run VDJtools commands for immune repertoire analysis.