bio-workflows-tcr-pipeline
Installation
SKILL.md
Version Compatibility
Reference examples tested with: MiXCR 4.6+, VDJtools 1.2.1+
Before using code patterns, verify installed versions match. If versions differ:
- CLI:
<tool> --versionthen<tool> --helpto confirm flags
If code throws ImportError, AttributeError, or TypeError, introspect the installed package and adapt the example to match the actual API rather than retrying.
TCR/BCR Analysis Pipeline
"Analyze my TCR/BCR repertoire sequencing data end-to-end" → Orchestrate MiXCR clonotype extraction, VDJtools diversity/repertoire analysis, Immcantation SHM and lineage analysis, and visualization of V/J gene usage and clonal dynamics.
Pipeline Overview
FASTQ → MiXCR align → Assemble → Export → VDJtools diversity → Visualization