seuratclusteringofallcells
Installation
SKILL.md
SeuratClusteringOfAllCells Process Configuration
Purpose
Performs coarse clustering on ALL cells (including T cells, B cells, and non-T/B cells) before cell type selection. This process identifies broad cell populations to enable subsequent T/B cell selection via TOrBCellSelection. Unlike SeuratClustering which works on already-selected T/B cells, this provides initial clustering on heterogeneous cell populations.
When to Use
- Mixed cell populations: When your data contains both T/B cells AND non-T/B cells
- Pre-selection clustering: Required upstream of
TOrBCellSelectionprocess - Broad cell type identification: To identify major cell lineages before fine-grained analysis
- TCR/BCR data analysis: When you have scRNA-seq + scTCR/scBCR data with mixed populations
- Do NOT use when: All cells are already T/B cells (use
SeuratClusteringinstead)
Configuration Structure
Process Enablement
[SeuratClusteringOfAllCells]
cache = true