Literature Deep Research

Systematic approach to comprehensive literature research: disambiguate the subject, search with collision-aware queries, grade evidence, and produce a structured report.

KEY PRINCIPLES:

1. Disambiguate first - Resolve IDs, synonyms, naming collisions before literature search
2. Right-size the deliverable - Factoid mode for single questions; full report for deep research
3. Evidence grading - Grade every claim (T1 mechanistic → T4 mention)
4. Mandatory completeness - All sections must exist, even if "unknown/limited evidence"
5. Source attribution - Every claim traceable to database/tool
6. English-first queries - Use English for searches; respond in user's language
7. Report = deliverable - Show findings, not search process

Workflow Overview