ai-scientist-v2-guide

Installation
SKILL.md

AI Scientist v2 Guide

Overview

AI-Scientist-v2 is an open-source system developed by Sakana AI with over 2,000 GitHub stars that automates the full scientific research pipeline -- from idea generation through experimentation to paper writing. Building on the original AI Scientist, version 2 introduces an agentic tree search approach that systematically explores the space of research ideas, designs and runs experiments, analyzes results, and produces workshop-level scientific papers with minimal human intervention.

The key innovation in v2 is the tree search mechanism. Rather than pursuing a single research direction linearly, the system maintains a tree of possible research trajectories. At each node, the agent can branch into multiple experimental variations, evaluate the results, and prune unpromising directions while doubling down on successful ones. This mirrors how experienced researchers navigate the research landscape -- exploring broadly at first, then focusing resources on the most promising leads.

AI-Scientist-v2 has demonstrated the ability to generate novel, valid research papers in machine learning subfields including diffusion models, language model training, and optimization. While the generated papers are currently at workshop acceptance level, the system represents a significant step toward autonomous scientific discovery and is an invaluable tool for researchers looking to automate the more mechanical aspects of their research workflow.

Installation and Setup

# Clone the repository
git clone https://github.com/SakanaAI/AI-Scientist-v2.git
cd AI-Scientist-v2

# Create a conda environment
conda create -n ai-scientist python=3.11
Related skills
Installs
6
GitHub Stars
217
First Seen
Mar 31, 2026