BioThings API Suite

Overview

BioThings is a family of high-performance biomedical annotation APIs developed at the Scripps Research Institute. The suite provides unified, up-to-date access to gene, variant, and chemical/drug annotations aggregated from dozens of authoritative sources. Three primary services cover the core entities in translational research:

• MyGene.info — Gene annotations from NCBI Entrez, Ensembl, UniProt, GO, KEGG, Reactome, and 20+ sources.
• MyVariant.info — Variant annotations from dbSNP, ClinVar, gnomAD, CADD, COSMIC, and 15+ sources.
• MyChem.info — Drug and chemical annotations from NDC, DrugBank, ChEMBL, FDA, PubChem, and 10+ sources.

All three share identical query syntax, require no authentication, and return JSON. Free for academic and commercial use.

Authentication

No authentication or API keys are required. All endpoints are open-access.

# No API key needed — just query directly
curl "https://mygene.info/v3/query?q=BRCA1&size=1"