Protein Interaction Network Analysis
Installation
SKILL.md
Protein Interaction Network Analysis
Comprehensive protein interaction network analysis using ToolUniverse tools. Analyzes protein networks through a 4-phase workflow: identifier mapping, network retrieval, enrichment analysis, and optional structural data.
Features
✅ Identifier Mapping - Convert protein names to database IDs (STRING, UniProt, Ensembl) ✅ Network Retrieval - Get interaction networks with confidence scores (0-1.0) ✅ Functional Enrichment - GO terms, KEGG pathways, Reactome pathways ✅ PPI Enrichment - Test if proteins form functional modules ✅ Structural Data - Optional SAXS/SANS solution structures (SASBDB) ✅ Fallback Strategy - STRING primary (no API key) → BioGRID secondary (if key available)