GWAS-to-Drug Target Discovery

Transform genome-wide association studies (GWAS) into actionable drug targets and repurposing opportunities.

Overview

This skill bridges genetic discoveries from GWAS with drug development by:

1. Identifying genetic risk factors - Finding genes associated with diseases
2. Assessing druggability - Evaluating which genes can be targeted by drugs
3. Prioritizing targets - Ranking candidates by genetic evidence strength
4. Finding existing drugs - Discovering approved/investigational compounds
5. Identifying repurposing opportunities - Matching drugs to new indications

Why This Matters

From Genetics to Therapeutics: GWAS has identified thousands of disease-associated variants, but most haven't been translated into therapies. This skill accelerates that translation.