TF Footprinting

TOBIAS Workflow

# 1. Correct Tn5 bias
tobias ATACorrect \
    --bam sample.bam \
    --genome genome.fa \
    --peaks peaks.bed \
    --outdir corrected/ \
    --cores 8

# 2. Calculate footprint scores
tobias FootprintScores \
    --signal corrected/sample_corrected.bw \
    --regions peaks.bed \
    --output footprints.bw \
    --cores 8