bio-structural-biology-modern-structure-prediction
Installation
SKILL.md
Modern Structure Prediction
Predict protein structures using state-of-the-art machine learning models. This covers cloud APIs, local installations, and interpretation of results.
Model Comparison
| Model | Complexes | Ligands | Speed | Access |
|---|---|---|---|---|
| AlphaFold3 | Yes | Yes | Slow | Server only (2025) |
| ESMFold | No | No | Fast | API or local |
| Chai-1 | Yes | Yes | Moderate | Local or API |
| Boltz-1 | Yes | Yes | Moderate | Local |
| ColabFold | No* | No | Moderate | Colab/local |
*ColabFold can predict complexes with AlphaFold-Multimer.