locus-to-gene-mapper-skill

Locus-to-Gene Mapper

Generate a reproducible locus-to-gene mapping for one trait (or a seed set of lead variants), with explicit evidence attribution and conservative confidence labels.

This skill is optimized for bioinformaticians who need executable, traceable mapping from variant signals to plausible causal genes.

Required Inputs

Provide at least one anchor source:

• trait_query (string), for example chronic obstructive pulmonary disease
• efo_id (string), for example EFO_0000341
• seed_rsids (list[string]), for example ["rs1873625", "rs7903146"]

Optional Inputs

• target_gene (string), optional gene of interest for highlighting in output
• show_child_traits (bool), default true
• phenotype_terms (list[string]), optional additional terms to include when finding anchors